PubMed COVID-19 Clinical Care

Phytoplankton assemblage responses to nitrogen following COVID-19 stay-in-place orders in western Long Island Sound (New York/Connecticut)

Saturday, February 03, 2024 - 4:00 AM

This study evaluated water quality, nitrogen (N), and phytoplankton assemblage linkages along the western Long Island Sound (USA) shoreline (Nov. 2020-Dec. 2021) following COVID-19 stay-in-place (SIP) orders through monthly surveys and N-addition

Motorcycle-related crashes before and during the COVID-19 pandemic: A comparative retrospective observational study from the Middle East

Saturday, February 03, 2024 - 4:00 AM

CONCLUSION: The overall burden of MCC increased during the pandemic, and the frequency of MCC involving commercial drivers surged significantly during the pandemic period as opposed to the non-work MCC, which predominated in the pre-pandemic period

CCL18, CHI3L1, ANG2, IL-6 systemic levels are associated with the extent of lung damage and radiomic features in SARS-CoV-2 infection

Saturday, February 03, 2024 - 4:00 AM

CONCLUSION: Data suggest a causal link between cytokines (risk factor), lung damage (mediator), and COVID-19 outcomes.

Insomnia is more likely to persist than remit after a time of stress and uncertainty: A longitudinal cohort study examining trajectories and predictors of insomnia symptoms

Saturday, February 03, 2024 - 4:00 AM

CONCLUSIONS: Insomnia was more likely to persist than remit over the first year of the COVID-19 pandemic. Addressing sleep reactivity and sleep effort appears critical for reducing insomnia persistence rates after times of stress and uncertainty.

An interdisciplinary course on computer-aided drug discovery to broaden student participation in original scientific research

Saturday, February 03, 2024 - 4:00 AM

We present a new highly interdisciplinary course in computer-aided drug discovery (CADD). This course was developed in response to a call for alternative pedagogical approaches during the COVID-19 pandemic, which caused the cancellation of a face-to

The efficacy and safety of vincristine, irinotecan and anlotinib in Epithelioid Sarcoma

Saturday, February 03, 2024 - 4:00 AM

CONCLUSIONS: The combination of irinotecan and Anlotinib as a salvage regimen may be considered another effective treatment option for refractory epithelioid sarcoma.

Infection-mediated immune response in SARS-CoV-2 breakthrough infection and implications for next-generation COVID-19 vaccine development

Saturday, February 03, 2024 - 4:00 AM

Post-vaccination infections, termed breakthrough infections, occur after the virus infection overcomes the vaccine-induced immune barrier. During the early stages of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron wave, high

Correction notice: Depression in older adults during the COVID-19 pandemic: a systematic review protocol

Saturday, February 03, 2024 - 4:00 AM

No abstract

Change of epidemiological characteristics of four respiratory viral infections in children before and during COVID-19 pandemic

Saturday, February 03, 2024 - 4:00 AM

CONCLUSIONS: Public health interventions for different pathogens are maximally effective. While positive rates for ADV, FLUA and FLUB decreased during the COVID-19 pandemic period, positive rates for RSV remained similar. In RSV and FLUA, off-season

In vitro broad-spectrum antiviral activity of MIT-001, a mitochondria-targeted reactive oxygen species scavenger, against severe acute respiratory syndrome coronavirus 2 and multiple zoonotic viruses

Saturday, February 03, 2024 - 4:00 AM

The COVID-19 pandemic caused by SARS-CoV-2 becomes a serious threat to global health and requires the development of effective antiviral therapies. Current therapies that target viral proteins have limited efficacy with side effects. In this study