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PubMed COVID-19 Clinical Care

24651 - 24660 of 44979 results found

Evolutionary safety of lethal mutagenesis driven by antiviral treatment

Date
Tuesday, August 08, 2023 - 4:00 AM
Description
Nucleoside analogs are a major class of antiviral drugs. Some act by increasing the viral mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however, may lead to an evolutionary safety concern. We define evolutionary