PubMed COVID-19 Clinical Care
23161 - 23170 of 44979 results found
A model-based strategy for the COVID-19 vaccine roll-out in the Philippines
Description
COVID-19 has affected millions of people worldwide, causing illness and death, and disrupting daily life while imposing a significant social and economic burden. Vaccination is an important control measure that significantly reduces mortality if
Family visits and depression among residential aged care residents: An integrative review
Description
CONCLUSION: Family visits ameliorated loneliness and depression among residents in aged care however, other factors such as culture, comorbidities and functional impairment, opportunities for socialisation and the social involvement of facility staff
Patient Centric Microsampling to Support Paxlovid Clinical Development: Bridging and Implementation
Description
Nirmatrelvir is a potent and selective SARS-CoV-2 main protease inhibitor. Nirmatrelvir co-packaged with ritonavir (as PAXLOVID^(TM) ) received FDA Emergency Use Authorization (EUA) on 22 Dec 2021 as an oral treatment for COVID-19 and subsequent NDA
The impact of COVID on bacterial sepsis
Description
CONCLUSION: Concurrent COVID-19 infection is associated with a significant increase in morbidity and mortality in patients with GP and GN BSIs. Patients with S. aureus BSIs with COVID-19 are more likely to develop shock and respiratory failure and
Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys
Description
Remdesivir 1 is an phosphoramidate prodrug that releases the monophosphate of nucleoside GS-441524 (2) into lung cells, thereby forming the bioactive triphosphate 2-NTP. 2-NTP, an analog of ATP, inhibits the SARS-CoV-2 RNA-dependent RNA polymerase
Developing an artificial intelligence-based headache diagnostic model from a clinic patients' dataset
Description
CONCLUSIONS: Our AI model demonstrated high diagnostic performance for migraine. If secondary headaches can be ruled out, the model can be a powerful tool for diagnosing migraine; however, further data collection and external validation are required
Exploring the Relationships Among (COVID)-19 Stress, Leisure Constraints, and Happiness for Adults During the (COVID)-19 Pandemic in Korea
Description
Objectives: The emergence of COVID-19 and its consequences has led to fears, worries, discomfort, depression, and anxiety for human beings worldwide. In this study, we examined the relationships among COVID-19 stress, leisure constraints, and
Hospitalization Among Patients Treated With Molnupiravir: A Retrospective Study of Administrative Data
Description
PURPOSE: Molnupiravir is an oral antiviral agent authorized for emergency use to treat mild to moderate cases of coronavirus disease 2019 (COVID-19) in adults at high risk for progression to severe clinical outcomes. This study aimed to describe
Generosity during the COVID-19 pandemic: The role of collective narcissism
Description
This study analyzes how a novel psychological factor-collective narcissism-affects giving behavior to national and international charities during the COVID-19 pandemic. We found that collective narcissists tended to keep more resources for themselves
