PubMed COVID-19 Clinical Care
1741 - 1750 of 44979 results found
Favipiravir, remdesivir, and lopinavir: metabolites, degradation products and their analytical methods
Description
Severe acute respiratory syndrome 2 (SARS-CoV-2) caused the emergence of the COVID-19 pandemic all over the world. Several studies have suggested that antiviral drugs such as favipiravir (FAV), remdesivir (RDV), and lopinavir (LPV) may potentially
Analyzing COVID-19 outbreaks: A methodological approach with Gaussian pulse models
Description
This method introduces a methodological approach for comprehensively analyzing COVID-19 outbreaks using Gaussian pulse models to assess transmission rates. Our methodology is designed to provide an in-depth understanding of the intricate dynamics
Feeling safe together vs. longing for touch. Affective, multisensorial contact in inclusive intra-active virtual/physical dance during the COVID-19 pandemic
Description
This article explores how feelings of safety were experienced through inclusive virtual/physical dance in relation to experiences of touch during the COVID-19 pandemic in Finland. The following are the measures I took to achieve the aim of this study
Enhanced SARS-CoV-2 case prediction using public health data and machine learning models
Description
CONCLUSION: Our proposed framework incorporates available public health metrics with operational data on the impact of testing, vaccination, and current viral variant mixtures in the population to provide a foundation for combining dynamic public
Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets
Description
New therapies and vaccines based on nucleic acids combined with an efficient nanoparticle delivery vehicle have a broad applicability for different disease indications. An alternative delivery technology for the successfully applied lipid
Implementation of a Frailty Care Bundle (FCB) Targeting Mobilisation, Nutrition and Cognitive Engagement to Reduce Hospital Associated Decline in Older Orthopaedic Trauma Patients: Pretest-Posttest Intervention Study
Description
CONCLUSION: It was feasible, during the Covid-19 pandemic, for multidisciplinary teams to implement elements of the FCB. Clinical facilitation supported teams to prioritise fundamental care above competing demands, but sustainability requires ongoing
Progress and challenges in the clinical evaluation of immune responses to respiratory mucosal vaccines
Description
INTRODUCTION: Following the coronavirus disease pandemic, respiratory mucosal vaccines that elicit both mucosal and systemic immune responses have garnered increasing attention. However, human physiological characteristics pose significant challenges
Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer
Description
Nanomaterials offer unique opportunities to engineer immunomodulatory activity. In this work, we report the Toll-like receptor agonist activity of a nanoscale adjuvant zeolitic imidazolate framework-8 (ZIF-8). The accumulation of ZIF-8 in endosomes
The impact of the 2022 spring COVID-19 booster vaccination programme on hospital occupancy in England: An interrupted time series analysis
Description
Regular booster vaccination programmes help protect the most vulnerable from COVID-19 and limit pressure on health systems. Existing studies find booster doses to be effective in preventing hospital admissions and deaths but focus on individual
