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PubMed COVID-19 Clinical Care

2561 - 2570 of 3460 results found

Pregnancy, infection, and epigenetic regulation: A complex scenario

Date
Saturday, June 03, 2023 - 4:00 AM
Description
A unique immunological condition, pregnancy ensures fetus from maternal rejection, allows adequate fetal development, and protects against microorganisms. Infections during pregnancy may lead to devastating consequences for pregnant women and fetuses

Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial

Date
Saturday, June 03, 2023 - 4:00 AM
Description
BACKGROUND: Activation of the triggering receptor expressed on myeloid cells-1 (TREM-1) pathway is associated with septic shock outcomes. Data suggest that modulation of this pathway in patients with activated TREM-1 might improve survival. Soluble