PRO-2000 exhibits SARS-CoV-2 antiviral activity by interfering with spike-heparin binding
Description
Here, we report on the anti-SARS-CoV-2 activity of PRO-2000, a sulfonated polyanionic compound. In Vero cells infected with the Wuhan, alpha, beta, delta or omicron variant, PRO-2000 displayed EC(50) values of 1.1 μM, 2.4 μM, 1.3 μM, 2.1 μM and 0.11
